توجه ! این یک نسخه آرشیو شده میباشد و در این حالت شما عکسی را مشاهده نمیکنید برای مشاهده کامل متن و عکسها بر روی لینک مقابل کلیک کنید : A double blind randomised controlled clinical trial comparing a novel anti-stain and calculus reducing dentifrice with a standard fluoride dentifrice

محمد بهبهانی
04-10-2013, 03:21 PM
a b s t r a c t
Objectives: This clinical trial tested the anti-stain efficacy at 3 and 6 months of a novel,
sodium polyaspartate-containing, anti-stain dentifrice. In addition, the efficacy of the new
dentifrice in controlling gingival inflammation and inhibition of calculus deposition was
Methods: Participants were recruited to this double blind randomised control clinical trial,
and allocated to either test or control groups. The presence of stain and calculus were entry
criteria. Measurements of stain, calculus and gingival inflammation were recorded using the
Shaw and Murray Stain score, Volpe-Manhold Calculus score and the Modified Gingival
Index respectively. Measurements were made at baseline, prior to the removal of stain and
calculus, and after 3 and 6 months. Missing data were imputed by and the outcomes were
analysed using univariate analysis.
Results: At three months, toothpaste containing sodium polyaspartate was better (difference
of mean 1.13 with SEM 0.57) than control for the control of dental stain ( p < 0.05). Stain
scores also showed a trend in favour of the test product (difference of mean 1.03 with SEM
0.78) at six months ( p > 0.05). There was no difference between toothpastes with respect to
calculus deposition or gingival inflammation.
Conclusions: Toothpaste containing sodium polyaspartate was more effective than a control
toothpaste at preventing deposition of dental stain for 3 months after professional tooth
cleaning but showed no significant effect at 6 months.
Clinical relevance: Sodium polyaspartate toothpaste was more effective than a control
toothpaste at preventing dental stain formation and maybe helpful in controlling staining
between episodes of scaling and polishing

a r t i c l e i n f o
Article history:
Received 9 November 2011
Received in revised form
1 November 2012
Accepted 10 December 2012
Sodium polyaspartate
Dental calculus